Carboxytherapy: Injected and Transdermal CO2, Two Generations

Two Routes

  1. Injected CO2 therapy: medical-grade CO2 micro-injected subdermally, triggering vasodilation and a hypoxia-reoxygenation response (the Bohr effect shifting oxygen dissociation) — used clinically for circulation and local fat appearance; a medical act.
  2. Non-invasive carbonated care: CO2 gels/masks delivering transdermal CO2 for mild vasodilation and warmth — the salon-channel “carbonated skincare” form, compliance depending on product class and claims.

The Honest Mechanism

CO2’s physiology (vasodilation, right-shifted oxygen dissociation) is established science; evidence strength in beauty varies by indication — circulation-type experiences are better supported, fat-loss claims weakly. Positioning claims as “circulation care” is the safe lane.

Where They Fit

Safety and Compliance

FAQ

Does the warmth from carbonated masks mean it works?

The warmth is CO2-driven vasodilation — real mechanism, real sensation; the chain to long-term outcomes varies by product and indication. “Circulation care” is the accurate frame.

Which route to choose?

License and indication decide: medical settings can run injectables as a specialty; salons are limited to non-invasive carbonated product lines.

Related Terms